Thermo Fisher Scientific RNF220 Polyclonal Antibody
RNF220 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 ELISA에 적합하며, 인간, 생쥐, 랫트 시료에 반응. 고순도의 Affinity Chromatography 정제, 50% glycerol 함유 PBS 용액 형태로 제공.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 267–566 of human RNF220 (NP_060620.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.86 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855719 |
Product Specific Information
Immunogen sequence:
PKSLLLSASI KREGESPTAS PHSSATDDLH HSDRYQTFLR VRANRQTRLN ARIGKMKRRK QDEGQREGSC MAEDDAVDIE HENNNRFEEY EWCGQKRIRA TTLLEGGFRG SGFIMCSGKE NPDSDADLDV DGDDTLEYGK PQYTEADVIP CTGEEPGEAK EREALRGAVL NGGPPSTRIT PEFSKWASDE MPSTSNGESS KQEAMQKTCK NSDIEKITED SAVTTFEALK ARVRELERQL SRGDRYKCLI CMDSYSMPLT SIQCWHVHCE ECWLRTLGAK KLCPQCNTIT APGDLRRIYL
Target Information
E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B. Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 promoting Wnt signaling (PubMed:25266658).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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