Thermo Fisher Scientific RNF220 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 267-566 of human RNF220 (NP_060620.2). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RNF220,uniProtId:Q5VTB9-1,ncbiNodeId:9606,antigenRange:267-566,antigenLength:566,antigenImageFileName:PA5-110308_RNF220_Q5VTB9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-110308_RNF220_Q5VTB9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.86 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2855719

Product Specific Information

Immunogen sequence: PKSLLLSASI KREGESPTAS PHSSATDDLH HSDRYQTFLR VRANRQTRLN ARIGKMKRRK QDEGQREGSC MAEDDAVDIE HENNNRFEEY EWCGQKRIRA TTLLEGGFRG SGFIMCSGKE NPDSDADLDV DGDDTLEYGK PQYTEADVIP CTGEEPGEAK EREALRGAVL NGGPPSTRIT PEFSKWASDE MPSTSNGESS KQEAMQKTCK NSDIEKITED SAVTTFEALK ARVRELERQL SRGDRYKCLI CMDSYSMPLT SIQCWHVHCE ECWLRTLGAK KLCPQCNTIT APGDLRRIYL

Target Information

E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B. Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 promoting Wnt signaling (PubMed:25266658).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.