Thermo Fisher Scientific ZHX2 Monoclonal Antibody (OTI2E11)
ZHX2 단백질을 인식하는 Mouse monoclonal antibody로 Western blot 및 IHC(P) 실험에 적합. Human 및 Mouse 반응성. 고순도 Affinity Chromatography 정제, 액상 형태로 제공. 연구용 전용 제품으로 안정적인 보관 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 595–837 of ZHX2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723796 |
Target Information
Zinc-fingers and homeobox (ZHX) proteins are transcription factors that interact with the activation domain of the A subunit of nuclear factor-Y (NF-YA). ZHX1–3 are ubiquitously expressed proteins found in various tissues. They act as transcriptional repressors and localize to the nucleus.
ZHX proteins contain two Cys(2)-His(2)-type zinc-finger motifs and five homeodomains (HDs), enabling homodimer and heterodimer formation. Dimerization is not required for repressor activity.
Hypermethylation-mediated silencing of ZHX2 is an epigenetic event associated with hepatocellular carcinoma (HCC).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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