Thermo Fisher Scientific COL22A1 Polyclonal Antibody
COL22A1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 인간 시료에 반응하며, 합성 펩타이드 면역원으로 제작되었습니다. 액상 형태로 PBS(2% sucrose) 용액에 보관되며, -20°C에서 보관 권장됩니다.
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Applications
- Western Blot (WB): 1.0 µg/mL
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal region of human COL22A1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2690625 |
Target Information
This gene encodes a member of the collagen family, contributing to the stabilization of myotendinous junctions and strengthening skeletal muscle attachments during contractile activity. It belongs to the fibril-associated collagens with interrupted triple helix (FACIT) subset, which associate with collagen fibers through their C-terminal collagenous domains and mediate protein-protein interactions through their N-terminal noncollagenous domains. The encoded protein is deposited in the basement membrane zone of the myotendinous junction, present at tissue junctions of muscles, tendons, heart, articular cartilage, and skin. Knockdown of the orthologous zebrafish gene induces muscular dystrophy by disrupting the myotendinous junction.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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