Thermo Fisher Scientific Seryl-tRNA synthetase Polyclonal Antibody
Seryl-tRNA synthetase 인식 폴리클로날 항체로 Western blot, IHC, ICC/IF에 사용 가능. Human에 반응하며 Rabbit IgG로 제작됨. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Seryl-tRNA synthetase. Recombinant protein control fragment (Product #RP-88815). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2647159 |
Product Specific Information
Immunogen sequence:
NVLSFDDLTA DALANLKVSQ IKKVRLLIDE AILKCDAERI KLEAERFENL REIGNLLHPS VPISNDEDVD NKVERIWGDC TVRKKYSHVD LVVMVDGFEG EKGAVVAGSR GYFLKGVLVF LEQALIQYAL
Highest antigen sequence identity to the following orthologs:
- Mouse: 95%
- Rat: 93%
Target Information
Seryl-tRNA synthetase (SerRS) catalyzes the attachment of serine to tRNA(Ser) in a two-step reaction:
- Serine is first activated by ATP to form Ser-AMP.
- Ser-AMP is then transferred to the acceptor end of tRNA(Ser).
It may also aminoacylate tRNA(Sec) with serine to form the misacylated L-seryl-tRNA(Sec), which is further converted into selenocysteinyl-tRNA(Sec).
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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