Thermo Fisher Scientific Claudin 6 Polyclonal Antibody
인간 Claudin 6 단백질을 인식하는 Rabbit Polyclonal 항체로 IHC 및 IHC(P) 실험에 적합합니다. 합성 펩타이드 면역원으로 제작되었으며, 액상 형태로 제공됩니다. PBS buffer(40% glycerol) 보존, -20°C 보관 조건. 연구용 전용 시약입니다.
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Applications
Immunohistochemistry (IHC)
Tested dilution: -Immunohistochemistry (Paraffin) (IHC (P))
Tested dilution: 1:20–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human Claudin 6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2688451 |
Target Information
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet.
This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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