Thermo Fisher Scientific Filamin B Polyclonal Antibody
Human Filamin B를 인식하는 Rabbit Polyclonal Antibody. IHC(P)에서 1:50–1:200 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제됨. PBS(40% 글리세롤) 버퍼에 보관, 단기 4°C, 장기 -20°C 저장 권장. 연구용으로만 사용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: 없음
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Filamin B. Recombinant protein control fragment (Product #RP-88633) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2641639 |
Product Specific Information
Immunogen sequence:
HGKVGEAGLL SVDCSEAGPG ALGLEAVSDS GTKAEVSIQN NKDGTYAVTY VPLTAGMYTL TMKYGGELVP HFPARVKVEP AVDTSRIKVF GPGIEGKDVF REATTDFTV
Sequence identity:
- Mouse: 92%
- Rat: 89%
Target Information
FOXK1 is expressed in these cells and regulates cell cycle progression through an interaction with its downstream target, the cyclin-dependent kinase inhibitor p21 (CIP).
Loss of FOXK1 in mice results in growth retardation and severe impairment in skeletal muscle regeneration following injury.
FOXK1 also shows expression in immature tissues of brain, eye, heart, lung, and thymus, and is predominantly expressed in many malignant tissues such as tumors of the brain, colon, and lymph node.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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