Thermo Fisher Scientific Filamin B Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human Filamin B. Recombinant protein control fragment (Product #RP-88633). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Filamin B,uniProtId:O75369-1,ncbiNodeId:9606,antigenRange:1145-1253,antigenLength:2602,antigenImageFileName:PA5-52129_Filamin_B_O75369-1_Rabbit.svg,antigenImageFileNamePDP:PA5-52129_Filamin_B_O75369-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2641639

Product Specific Information

Immunogen sequence: HGKVGEAGLL SVDCSEAGPG ALGLEAVSDS GTKAEVSIQN NKDGTYAVTY VPLTAGMYTL TMKYGGELVP HFPARVKVEP AVDTSRIKVF GPGIEGKDVF REATTDFTV

Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 89%.

Target Information

FOXK1 is expressed in these cells and regulates cell cycle progression through an interaction with its downstream target the cyclin-dependent kinase inhibitor p21 (CIP). Loss of FOXK1 in mice results in growth retardation and a severe impairment in skeletal muscle regeneration following injury. FOXK1 also shows expression in immature tissues of brain, eye, heart, lung and thymus. It also is predominantly expressed in many malignant tissues, such as tumors of the brain, colon and lymph node.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.