Thermo Fisher Scientific DTYMK Polyclonal Antibody
Human 및 Mouse 반응성을 가진 Rabbit Polyclonal DTYMK 항체로 Western blot과 Immunoprecipitation에 적합. 항원 친화 크로마토그래피로 정제되어 1 mg/mL 농도의 액상 형태로 제공. DNA 합성 관련 연구 및 Thymidylate kinase 기능 분석에 활용 가능.
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Thermo Fisher Scientific DTYMK Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:2,000–1:10,000
- Immunoprecipitation (IP): 20 µL/mg of lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A region between residue 162 to 212 of human Thymidylate kinase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7.0–8.0 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Thymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and serves as an intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5-Fluorouracil (5-FU), a chemotherapeutic drug used for several solid tumors.
The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle mutant (cdc8). DTYMK mRNA levels and enzyme activities are regulated at the level of cell cycle and cell growth pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- A305-652A_DTYMK_P23919-1_Rabbit_PDP.jpeg
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