Thermo Fisher Scientific LRR1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human LRR1. Recombinant protein control fragment (Product #RP-104088). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LRR1,uniProtId:Q96L50-1,ncbiNodeId:9606,antigenRange:339-412,antigenLength:414,antigenImageFileName:PA5-64236_LRR1_Q96L50-1_Rabbit.svg,antigenImageFileNamePDP:PA5-64236_LRR1_Q96L50-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2643485

Product Specific Information

Immunogen sequence: GSHIIPFHLC QDLDTAKICV CGRFCLNSFI QGTTTMNLHS VAHTVVLVDN LGGTEAPIIS YFCSLGCYVN SSDM

Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 82%.

Target Information

May negatively regulate the 4-1BB-mediated signaling cascades which result in the activation of NK-kappaB and JNK1. Probable substrate recognition subunit of an ECS (Elongin BC- CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.