Thermo Fisher Scientific CHOP Polyclonal Antibody
CHOP 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, 인간 시료에 반응합니다. ICC/IF 실험에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 기반 저장용액과 40% 글리세롤을 포함하며, 연구용으로만 사용됩니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein corresponding to Human CHOP. Recombinant protein control fragment (Product # RP-103961) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856878 |
Product Specific Information
Immunogen sequence:
AESLPFSFGT LSSWELEAWY EDLQEVLSSD ENGGTYVSPP GNEEEESKIF TTLDPASLAW LTEEEPEPAE VTSTSQ
Target Information
GADD153 is a small nuclear protein that dimerizes with transcription factors C/EBP alpha and beta. Once dimerized, this complex inhibits the normal binding and function of C/EBP to classical binding sites. Conversely, the C/EBP–GADD153 dimer gains binding activity to other non-classical, stress-related targets.
Under normal cellular conditions, GADD153 is not expressed at detectable levels but is highly upregulated during cellular or ER stress. Examples of inducing stress include treatment with tunicamycin, nutrient starvation, and reducing agents that interfere with calcium flux across the ER membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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