Thermo Fisher Scientific LMBRD1 Polyclonal Antibody
Thermo Fisher Scientific의 LMBRD1 폴리클로날 항체는 인간 및 마우스 반응성을 가지며 Western blot, ICC/IF, ELISA에 적합합니다. 재조합 단백질 항원을 기반으로 제작되었으며 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications 및 권장 희석 배율
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing sequence corresponding to amino acids 220–300 of human LMBRD1 (NP_0608383) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.39 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806233 |
Product Specific Information
- Immunogen sequence: PLNLIKGTRS AAYERLENTE DIEEVEQHIQ TIKSKSKDGR PLPARDKRAL KQFEERLRTL KKRERHLEFI ENSWWTKFCG A
- Positive Samples: U-87MG, HeLa, Mouse brain, Mouse lung, Mouse spleen
- Cellular Location: Lysosome membrane, Multi-pass membrane protein
Target Information
LMBRD1, also known as NESI (nuclear export signal-interacting protein), is a lysosomal membrane protein involved in the transport and metabolism of cobalamin. It interacts with the large form of the hepatitis delta antigen and may be required for nucleocytoplasmic shuttling of the hepatitis delta virus. Mutations in LMBRD1 are associated with vitamin B12 metabolism disorder, homocystinuria-megaloblastic anemia complementation type F (cblF).
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: PA5-90773_LMBRD1_Q9NUN5-1_Rabbit.svg, PA5-90773_LMBRD1_Q9NUN5-1_Rabbit_PDP.jpeg)
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