Thermo Fisher Scientific EWSR1 Polyclonal Antibody
EWSR1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC, IP 등에 적합. Human 시료 반응성. 항원 친화 크로마토그래피로 정제되었으며, 장기 보관 시 -20°C에서 보관 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:400 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Immunoprecipitation (IP) | 1–5 µL/mg of lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived Human EWSR1 fragment |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography, Protein A |
| Storage Buffer | PBS, pH 7 |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2866923 |
Target Information
This gene encodes a multifunctional protein involved in gene expression, cell signaling, and RNA processing and transport.
The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain.
Chromosomal translocations between this gene and genes encoding transcription factors result in chimeric proteins implicated in tumorigenesis.
These chimeric proteins typically contain the N-terminal activation domain of EWSR1 fused to the C-terminal DNA-binding domain of a transcription factor.
Mutations or translocations of this gene are associated with Ewing sarcoma, neuroectodermal tumors, and other cancers.
Alternative splicing produces multiple transcript variants, and related pseudogenes are found on chromosomes 1 and 14.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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