Thermo Fisher Scientific TNFRSF21 Monoclonal Antibody (7D9)
인간 TNFRSF21 단백질을 인식하는 Mouse IgG1 단일클론 항체. ELISA에 최적화되어 있으며, 액상 형태로 제공. PBS(pH 7.4) 버퍼에 보존제 없이 구성되어 있음. -20°C 보관, 동결/해동 반복 피해야 함. 연구용으로만 사용 가능.
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Applications
- ELISA (ELISA): Tested dilution 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 7D9 |
| Immunogen | TNFRSF21 (AAH17730.1, 89 a.a. – approximately 170 a.a) partial recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
SSCPVGTFTR HENGIEKCHD CSQPCPWPMI EKLPCAALTD RECTCPPGMF QSNATCAPHT VCPVGWGVRK KGTETEDVRC KQ
Target Information
DR6 is widely expressed in human tissues and cell lines. The ligand for DR6 has not been identified. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNF-R1 and Fas. Several novel death receptors including DR3, DR4, and DR5 were recently identified. A new death domain containing receptor in the TNFR family was cloned recently and termed DR6 (death receptor-6). Like TNF-R1, DR6 interacts with the death domain-containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-kappa-B and JNK.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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