Thermo Fisher Scientific RORB Monoclonal Antibody (OTI1G1), TrueMAB
Human RORB 단백질(aa 1-260)에 특이적인 Mouse IgG1 단클론 항체로, WB(1:2000) 및 IHC-P(1:150)에 적합. 액상 형태이며 PBS/BSA/glycerol buffer에 보관. 신경계 발달 및 생체 리듬 연구용으로 최적화된 TrueMAB 항체.
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Applications
- Western Blot (WB): 1:2,000
- Immunohistochemistry (Paraffin) (IHC-P): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–260 of human RORB produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Retinoid-related orphan receptor beta (ROR beta), a NR1 thyroid hormone receptor, affects the development and functioning of the central nervous system, including sensory input integration and circadian timing.
Disruption of ROR beta in mice results in juvenile ataxia, retinal degeneration, circadian activity abnormalities, and delayed onset of male fertility.
ROR beta binds to monomeric response elements containing the sequence AnnTAGGTCA as a monomer.
An alternatively spliced isoform, ROR beta2, has been isolated from rats, and its expression is confined to the pineal gland and retina.
ROR beta2 shares common DNA- and putative ligand-binding domains with wild-type ROR beta but has a distinct amino-terminal domain.
ROR beta expression has been documented in various regions of the mouse brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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