Thermo Fisher Scientific PRPK Polyclonal Antibody
PRPK 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB와 ELISA에 적합합니다. Human, Mouse, Rat에 반응하며 핵 내 위치 단백질 검출에 사용됩니다. 고순도 Affinity Chromatography 정제, -20°C 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1–253 of human TP53RK (NP_2910283) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.37 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805936 |
Product Specific Information
- Immunogen sequence:
MAAARATTPA DGEEPAPEAE ALAAARERSS RFLSGLELVK QGAEARVFRG RFQGRAAVIK HRFPKGYRHP ALEARLGRRR TVQEARALLR CRRAGISAPV VFFVDYASNC LYMEEIEGSV TVRDYIQSTM ETEKTPQGLS NLAKTIGQVL ARMHDEDLIH GDLTTSNMLL KPPLEQLNIV LIDFGLSFIS ALPEDKGVDL YVLEKAFLST HPNTETVFEA FLKSYSTSSK KARPVLKKLD EVRLRGRKRS MVG - Positive Samples: HT-29, BxPC3, 293T, HeLa, Jurkat, Mouse testis, Mouse thymus, Rat testis
- Cellular Location: Nucleus
Target Information
Component of the EKC/KEOPS complex required for threonylcarbamoyl group formation on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
TP53RK has ATPase activity within the EKC/KEOPS complex and supports the catalytic subunit OSGEP.
Functions as an atypical protein kinase that phosphorylates Ser-15 of p53/TP53, contributing to its activation.
[UniProt]
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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