Thermo Fisher Scientific LAS1L Polyclonal Antibody
인간 LAS1L 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:1,000~1:2,500 희석 비율로 검증됨. 60S 리보솜 소단위체 생합성 연구에 적합하며, 항원 친화 크로마토그래피로 정제됨. PBS 기반 완충액에 40% 글리세롤 포함, 장기 보관 시 -20°C 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human LAS1L. Recombinant protein control fragment (Product # RP-103404) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2643293 |
Product Specific Information
Immunogen sequence:
VRWDTFPLGR MPGQTEDPAE LMLENYDTMY LLDQPVLEQR LEPSTCKTDT LGLSCGVGSG NCSNSSSSNF EGLLWSQGQL HGLKTG
Highest antigen sequence identity:
- Mouse: 74%
- Rat: 67%
Target Information
LAS1L is involved in the biogenesis of the 60S ribosomal subunit and is required for maturation of the 28S rRNA.
It functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex, which is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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