Thermo Fisher Scientific LAS1L Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:2,500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human LAS1L. Recombinant protein control fragment (Product #RP-103404). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LAS1L,uniProtId:Q9Y4W2-1,ncbiNodeId:9606,antigenRange:645-730,antigenLength:734,antigenImageFileName:PA5-63962_LAS1L_Q9Y4W2-1_Rabbit.svg,antigenImageFileNamePDP:PA5-63962_LAS1L_Q9Y4W2-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2643293

Product Specific Information

Immunogen sequence: VRWDTFPLGR MPGQTEDPAE LMLENYDTMY LLDQPVLEQR LEPSTCKTDT LGLSCGVGSG NCSNSSSSNF EGLLWSQGQL HGLKTG

Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 67%.

Target Information

Involved in the biogenesis of the 60S ribosomal subunit. Required for maturation of the 28S rRNA. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.