Thermo Fisher Scientific NLRC4 Polyclonal Antibody
Rabbit polyclonal antibody specific to human NLRC4 protein. Validated for ICC/IF applications. Supplied as liquid, unconjugated form with 0.1 mg/mL concentration. Suitable for research use in innate immune response studies.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Category | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence (range: 660–753). Recombinant protein control fragment: Product #RP-110107 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3092077 |
Product Specific Information
Immunogen sequence:
RTLEVTLRDF SKLNKQDIRY LGKIFSSATS LRLQIKRCAG VAGSLSLVLS TCKNIYSLMV EASPLTIEDE RHITSVTNLK TLSIHDLQNQ RLPG
Antigen sequence identity:
- Mouse: 73%
- Rat: 79%
Target Information
NLRC4 (NLR family CARD domain-containing 4) encodes a member of the caspase recruitment domain-containing NLR family. These proteins play essential roles in innate immune responses to pathogenic organisms, tissue damage, and cellular stress. Mutations in this gene are associated with autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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