Thermo Fisher Scientific 53BP2 Polyclonal Antibody

Thermo Fisher Scientific 53BP2 Polyclonal Antibody

Applications

• Western Blot (WB)

Tested Dilution: 1:500–1:2,000
Publications: - References

Product Specifications

Product Specific Information

Immunogen sequence:
RALKGHVEQK RLSNGKLVEE IEQMNNLFQQ KQRELVLAVS KVEELTRQLE MLKNGRIDSH HDNQSAVAEL DRLYKELQLR NKLNQEQNAK LQQQRECLNK RNSEVAVMDK RVNELRDRLW KKKAALQQKE N

Target Information

Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions.
Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo.
Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis.
Impede cell cycle progression at G2/M.
Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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