Thermo Fisher Scientific 53BP2 Polyclonal Antibody
53BP2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 최적화된 고품질 항체로, 세포 성장 및 apoptosis 연구에 활용 가능. 액상 형태로 제공되며 -20°C 보관 필요.
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- PA5110511
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- pk
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Thermo Fisher Scientific 53BP2 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:2,000
Publications: - References
Product Specifications
| 항목 | 내용 |
|---|---|
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 200–330 of TP53BP2 (NP_0010268552) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.4 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855922 |
Product Specific Information
Immunogen sequence:
RALKGHVEQK RLSNGKLVEE IEQMNNLFQQ KQRELVLAVS KVEELTRQLE MLKNGRIDSH HDNQSAVAEL DRLYKELQLR NKLNQEQNAK LQQQRECLNK RNSEVAVMDK RVNELRDRLW KKKAALQQKE N
Target Information
Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions.
Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo.
Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis.
Impede cell cycle progression at G2/M.
Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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