Thermo Fisher Scientific PON1 Monoclonal Antibody (OTI2D4), Biotin, TrueMAB
인간 PON1 단백질을 인식하는 Biotin 결합 단클론 항체로, ELISA 및 Luminex 분석에 적합합니다. 고순도의 Affinity chromatography 정제 제품이며, 안정적인 PBS/BSA/glycerol 완충액에 보존됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| ELISA | 1:250–1:1,000 |
| Luminex | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D4 |
| Immunogen | Full length human recombinant protein of human HPGD produced in HEK293T cell |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 10 mg/mL BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
The paraoxonase (PON) gene family in humans has three members: PON1, PON2, and PON3, located on chromosome 7q21.3–22.1.
PON1 is primarily synthesized in the liver and secreted into plasma, where it associates with high-density lipoproteins (HDL).
It hydrolyzes active metabolites of several organophosphorus insecticides (e.g., chlorpyrifos oxon, diazoxon) and nerve agents such as sarin, soman, and VX.
PON1 polymorphism has been implicated in neurodegeneration and may be an independent risk factor for Parkinson’s disease.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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