Thermo Fisher Scientific E. coli (strain K12) PdeH Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:2,000-1:10,000

-

Product Specifications

Species Reactivity

Bacteria

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Escherichia coli Cyclic di-GMP phosphodiesterase PdeH protein (1-255aa)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

4.915 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.03% ProClin 300

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Wet ice

RRID

AB_2902210

Product Specific Information

This antibody has been tested in direct-ELISA

Target Information

Involved in the control of the switch from cell motility to adhesion via regulation of cellular levels of cyclic-di-GMP (c-di-GMP) (PubMed:18765794). Part of a signaling cascade that regulates curli biosynthesis. The cascade is composed of two c-di-GMP control modules, in which c-di-GMP controlled by the DgcEPdeH pair (module I) regulates the activity of the DgcMPdeR pair (module II), which in turn regulates activity of the transcription factor MlrA and expression of the master biofilm regulator csgD (PubMed:23708798). Effect on flagella is controlled via the c-di-GMP-binding flagellar brake protein YcgR (PubMed:18765794).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.