Thermo Fisher Scientific PPP1CB Polyclonal Antibody
PPP1CB 단백질에 특이적인 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, IP 등 다양한 응용에 적합하며, 항원 친화 크로마토그래피로 정제됨. 인간 및 여러 종에서 반응 예측됨. 연구용으로만 사용 가능.
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Thermo Fisher Scientific PPP1CB Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 280 and the C-terminus (residue 327) of Human Protein Phosphatase 1, Catalytic Subunit, Beta Isoform |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections
- Based on 100% sequence identity, predicted to react with Mouse, Rat, Xenopus laevis, Xenopus tropicalis, Chicken, Bovine, Dog, Rabbit, Pig, and Orangutan
Target Information
The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine-specific protein phosphatase involved in regulating various cellular processes such as:
- Cell division
- Glycogen metabolism
- Muscle contractility
- Protein synthesis
- HIV-1 viral transcription
Mouse studies suggest PP1 functions as a suppressor of learning and memory. Two alternatively spliced transcript variants encoding distinct isoforms have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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