Thermo Fisher Scientific TRIP230 Polyclonal Antibody
Recombinant Human TRIP230 항원을 면역원으로 제작된 Rabbit Polyclonal Antibody. 인간 시료 반응성 확인됨. ICC/IF에 0.25–2 µg/mL 농도로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 4°C 단기 보관 및 -20°C 장기 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human TRIP230 (Recombinant protein control fragment: Product #RP-107763) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663363 |
Product Specific Information
Immunogen sequence:
MLDDVQKKLMS LANSSEGKVD KVLMRNLFIG HFHTPKNQRH EVLRLMGSIL GVRREEMEQL FHDDQGSVTR WMTGWLGGGS KSVPNTPLRP NQQSV
Highest antigen sequence identity to the following orthologs:
- Mouse: 91%
- Rat: 92%
Target Information
The Trip230 gene encodes a protein of 1,978 amino acids with an estimated molecular mass of 230 kDa. The gene is located on chromosome 14q31, a region associated with genetic alterations and thyroid hormone response abnormalities.
Trip230 interacts with Rb and thyroid hormone receptor (TR) via distinct domains. Complex formation with Rb occurs in a hormone-independent manner, while complex formation with TR is thyroid hormone-dependent. After T3 treatment, Trip230 is phosphorylated and translocated to the nucleus, suggesting phosphorylation is important for nuclear transport.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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