Thermo Fisher Scientific GPR123 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human GPR123. Recombinant protein control fragment (Product #RP-99985). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GPR123,uniProtId:Q86SQ6-3,ncbiNodeId:9606,antigenRange:361-462,antigenLength:560,antigenImageFileName:PA5-60114_GPR123_Q86SQ6-3_Rabbit.svg,antigenImageFileNamePDP:PA5-60114_GPR123_Q86SQ6-3_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2642161

Product Specific Information

Immunogen sequence: PCKMTNLQAA QGHASCLSPA TPCCAKMHCE PLTADEAHVH LQEEGAFGHD PHLHGCLQGR TKPPYFSRHP AEEPEYAYHI PSSLDGSPRS SRTDSPPSSL DG

Highest antigen sequence identity to the following orthologs: Mouse - 70%, Rat - 68%.

Target Information

G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR123 (G protein-coupled receptor 123) is a 1,279 amino acid multi-pass membrane protein belonging to the G-protein coupled receptor 2 family and LN-TM7 subfamily. Existing as two alternatively spliced isoforms, GPR123 functions as an orphan receptor that is expressed in adult and fetal brain, and in adult spinal cord. The gene encoding GPR123 maps to human chromosome 10q26.3 and mouse chromosome 7 F4.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.