Thermo Fisher Scientific GPR123 Polyclonal Antibody
Human GPR123 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:50–1:200 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 0.2 mg/mL 농도의 액상 형태. 뇌 및 척수 조직 연구에 적합한 연구용 항체.
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Applications
Tested Applications and Dilutions
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GPR123. Recombinant protein control fragment (Product # RP-99985) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2642161 |
Product Specific Information
Immunogen sequence:
PCKMTNLQAA QGHASCLSPA TPCCAKMHCE PLTADEAHVH LQEEGAFGHD PHLHGCLQGR TKPPYFSRHP AEEPEYAYHI PSSLDGSPRS SRTDSPPSSL DG
Sequence identity:
- Mouse: 70%
- Rat: 68%
Target Information
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors or 7TM receptors, are a large superfamily of proteins involved in a variety of stimulus-response pathways. They translate extracellular signals into intracellular responses via G protein activation and respond to signaling molecules such as hormones and neurotransmitters.
GPR123 (G protein-coupled receptor 123) is a 1,279 amino acid multi-pass membrane protein belonging to the G-protein coupled receptor 2 family and LN-TM7 subfamily. It exists as two alternatively spliced isoforms and functions as an orphan receptor expressed in adult and fetal brain, and adult spinal cord. The gene encoding GPR123 maps to human chromosome 10q26.3 and mouse chromosome 7 F4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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