Thermo Fisher Scientific BTBD12 Polyclonal Antibody
BTBD12 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 적합하며, 항원 친화 크로마토그래피로 정제됨. 인간 시료 반응성, 액상 형태, 4°C 보관.
- 판매단위
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Applications
Western Blot (WB)
- Assay-dependent
Immunoprecipitation (IP)
- 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1650 and 1700 of human BTB (POZ) domain containing 12 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
This gene encodes a structure-specific endonuclease subunit. The encoded protein contains a central BTB domain and forms a multiprotein complex with ERCC4(XPF)-ERCC1, MUS81-EME1, and SLX1 endonucleases. It also associates with MSH2/MSH3 mismatch repair complex, telomere binding complex TERF2(TRF2)-TERF2IP(RAP1), protein kinase PLK1, and uncharacterized protein C20orf94.
The multiprotein complex is required for repair of specific DNA lesions and is critical for cellular responses to replication fork failure. The encoded protein acts as a docking platform for the assembly of multiple structure-specific endonucleases.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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