Thermo Fisher Scientific GNAI3 Polyclonal Antibody
GNAI3 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat 시료에 반응하며, Protein A로 정제된 고순도 항체입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human GNAI3, amino acids 241–354 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Heterotrimeric G proteins relay information from cell surface receptors to intracellular effectors. Each receptor detects specific extracellular stimuli such as photons, pheromones, odorants, hormones, or neurotransmitters, while effectors like adenyl cyclase generate intracellular messengers.
In mammals, G protein alpha, beta, and gamma subunits are encoded by at least 16, 4, and 7 genes, respectively. The alpha subunits bind and hydrolyze GTP, regulating effector activity.
Four classes of Galpha subunits exist: Gs, Gi, Gq, and Galpha 12/13. The Gi class includes alpha subunits susceptible to pertussis toxin modification (Galpha i-1, i-2, i-3, o, t1, t2, z, gust), with Galpha i subtypes functioning to open atrial potassium channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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