Thermo Fisher Scientific FBXW12 Polyclonal Antibody
Human FBXW12 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:500~1:1,000 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 단백질 유비퀴틴화 연구용으로 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FBXW12. Recombinant protein control fragment (Product #RP-96422) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641560 |
Product Specific Information
Immunogen sequence:
SPVQEFHFSN LVTLPQMHLA ITMDWKKTIK VWNCQDRDAL AVLPMPQPCY CMEAYLTKDG PFLMVGDAAG DIYTFTLPGL RDVSKVTAFQ Y
Highest antigen sequence identity to the following orthologs:
- Mouse: 46%
- Rat: 45%
Target Information
Members of the F-box protein family, such as FBXW12, are characterized by an approximately 40-amino acid F-box motif.
SCF complexes, formed by SKP1 (MIM 601434), cullin (CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases.
F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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