
Thermo Fisher Scientific SPANXB1 Monoclonal Antibody (OTI1E11), TrueMAB
Thermo Fisher Scientific의 SPANXB1 단클론 항체(OTI1E11)는 인간 시료에 반응하며 Western blot과 IHC(Paraffin)에 적합합니다. Affinity chromatography로 정제된 액상 항체로, 1 mg/mL 농도이며 PBS/BSA/glycerol buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E11 |
| Immunogen | Full length human recombinant protein of SPANXB1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa.
This gene is a member of the SPANX family of cancer/testis-associated genes, located in a cluster on chromosome X.
SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments.
The SPANXB genes contain an additional 18 nt in their coding region compared to most family members.
Although the encoded protein includes nuclear localization signals, it primarily localizes to cytoplasmic droplets of ejaculated spermatozoa, serving as a biochemical marker for studying sperm structure and spermatogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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