Thermo Fisher Scientific CYP2E1 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Target Information

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines, which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in processes such as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.