Thermo Fisher Scientific TP53RK Monoclonal Antibody (OTI5B2), TrueMAB
TP53RK 단백질을 인식하는 Mouse 단일클론 항체로 Western blot 및 IHC에 적합. 인간 시료 반응성, TrueMAB 포맷. 고순도 Affinity chromatography 정제 및 안정적 액상 형태. 연구용으로만 사용 가능.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5B2 |
| Immunogen | Full length human recombinant protein of human TP53RK produced in E.coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Component of the EKC/KEOPS complex required for formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (PubMed:22912744, PubMed:27903914).
The complex is involved in transferring the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.
TP53RK exhibits ATPase activity within the EKC/KEOPS complex and supports the catalytic subunit OSGEP.
An atypical protein kinase that phosphorylates Ser-15 of p53/TP53 and may participate in its activation (PubMed:11546806).
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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