Thermo Fisher Scientific NAK Polyclonal Antibody, Biotin
TBK1 단백질을 인식하는 Rabbit Polyclonal Antibody로 Biotin 결합형입니다. Western blot, IHC, ELISA, IP 등 다양한 실험에 사용 가능하며, 고순도 친화 크로마토그래피로 정제되었습니다. 인체, 마우스, 랫트 반응성 보유.
- 카탈로그번호
- TBK1-BIOTIN
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific NAK Polyclonal Antibody, Biotin
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide taken within second intracellular loop of human TBK1 protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TBK1 serine/threonine kinase is a member of the IKK family and is involved in NF-kappa B activation and IRF3 signaling. TBK1 acts as a ubiquitous transcription factor and plays an essential role in gene expression during immune and inflammatory responses. NF-kB mediates the expression of numerous genes in response to extracellular stimuli and is regulated by IKB proteins. Phosphorylation of IKB by the IKK complex leads to IKB degradation and NF-kB activation. TBK1 (also known as NAK or T2K) activates IKK beta through direct phosphorylation and functions upstream of NIK and the IKK complex. It is critical in protecting embryonic liver from apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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