Thermo Fisher Scientific HACE1 Monoclonal Antibody (OTI10D3), TrueMAB
HACE1 단백질을 인식하는 Mouse IgG2b 단일클론 항체로, Western blot에 적합합니다. HEK293T 세포에서 발현된 full-length human HACE1 항원을 면역원으로 사용했습니다. 1 mg/mL 농도의 액상 형태이며, PBS/BSA/glycerol buffer에 보관됩니다. 연구용 전용 제품입니다.
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- TA810113
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- pk
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10D3 |
| Immunogen | Full length human recombinant protein of human HACE1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division. Specifically interacts with GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens. May also act as a transcription regulator via its interaction with RARB.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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