Thermo Fisher Scientific KLF17 Polyclonal Antibody
KLF17 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ELISA에 사용 가능. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제되었으며 PBS buffer에 0.02% sodium azide 포함. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL | - |
| ELISA | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | 17 amino acid peptide near the carboxy terminus of human KLF17 (within the last 50 amino acids of KLF17) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2718692 |
Target Information
KLF17 is a transcription repressor that binds to the promoter of target genes and prevents their expression.
Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer.
Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and represses its expression.
May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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