Thermo Fisher Scientific IL24 Monoclonal Antibody (4B6)
인간 IL24 단백질에 특이적인 Mouse 모노클론 항체로 Western blot, ELISA, IP 등에 사용 가능. Affinity chromatography로 정제된 액상 형태이며, PBS buffer에 보존제 없이 제공. IL-24 관련 JAK/STAT 신호 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 10 µg/mL |
| Immunoprecipitation (IP) | 1–5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4B6 |
| Immunogen | IL24 (AAH09681, 58–167 a.a) partial recombinant protein with GST tag (MW of GST tag alone: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
GPCQVKGVVP QKLWEAFWAV KDTMQAQDNI TSARLLQQEV LQNVSDAESC YLVHTLLEFY LKTVFKNYHN RTVEVRTLKS FSTLANNFVL IVSQLQPSQE NEMFSIRDSA
Target Information
Interleukin 24 (IL-24), also known as melanoma differentiation-associated gene-7 (mda-7), encodes a secreted protein homologous to the IL-10 family of cytokines. Human IL-24 is secreted by activated peripheral blood mononuclear cells and interacts with receptors IL-22R1/IL-20R2 and IL-20R1/IL-20R2, activating JAK/STAT signaling pathways.
Mda-7/IL-24 selectively induces growth suppression, apoptosis, and radiosensitization in malignant gliomas in a p53-independent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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