Thermo Fisher Scientific CMKLR1 Polyclonal Antibody
CMKLR1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간, 마우스, 랫트에 반응하며 WB 및 ICC/IF에 적합. 고순도 친화 크로마토그래피 정제, 액상 형태로 안정적 저장 가능.
- 카탈로그번호
- PA5118841
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CMKLR1 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CMKLR1 (Accession Q99788), corresponding to amino acid residues F229–L279 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903341 |
Product Specific Information
Antibody detects endogenous levels of total CMKLR1.
Target Information
Chemokine-like receptor 1 (CMKLR1) is a receptor for the chemoattractant adipokine chemerin (RARRES2) and for the omega-3 fatty acid derived molecule resolvin E1.
Interaction with RARRES2 induces activation of intracellular signaling molecules such as SKY, MAPK1/3 (ERK1/2), MAPK14 (P38MAPK), and PI3K, leading to multifunctional effects including reduction of immune responses, enhancement of adipogenesis, and angiogenesis.
Resolvin E1 down-regulates cytokine production in macrophages by reducing activation of MAPK1/3 (ERK1/2) and NF-kappa-B.
CMKLR1 positively regulates adipogenesis and adipocyte metabolism and acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR, and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-118841_CMKLR1_Q99788-1_Rabbit.svg, PA5-118841_CMKLR1_Q99788-1_Rabbit_PDP.jpeg)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.