Thermo Fisher Scientific RRAGC/RagC Polyclonal Antibody
RRAGC/RagC 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체입니다. Western blot 및 Immunoprecipitation에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 인간에 반응하며, 액상 형태로 제공되고 4°C에서 보관합니다.
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Applications
Western Blot (WB)
- Assay-dependent
Immunoprecipitation (IP)
- 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 349 to 399 of Human Ras-Related GTP Binding C |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
RRAGC (Ras-related GTP-binding protein C) is a monomeric guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
RRAGC forms a heterodimer with RRAGA and RRAGB and is primarily localized to the cytoplasm.
It cycles between an inactive GTP-bound and an active GDP-bound form.
In its active form, RRAGC participates in the re-localization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB — a crucial step in the activation of the TOR signaling cascade by amino acids.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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