Thermo Fisher Scientific CENPH Polyclonal Antibody
Thermo Fisher Scientific의 CENPH Polyclonal Antibody는 인간 CENPH 단백질을 인식하는 토끼 IgG 폴리클로날 항체입니다. Western blot 및 ICC/IF에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. PBS/glycerol 버퍼에 보관하며 연구용으로 사용됩니다.
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Thermo Fisher Scientific CENPH Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CENPH (Accession Q9H3R5), corresponding to amino acid residues M1–D38 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852826 |
Product Specific Information
Antibody detects endogenous levels of total CENPH.
Target Information
Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation.
The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase.
It localizes outside of centromeric heterochromatin (where CENP-B is localized) and inside the kinetochore corona (where CENP-E is localized during prometaphase).
This protein can bind to itself, as well as to CENP-A, CENP-B, or CENP-C.
Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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