Thermo Fisher Scientific GTF2B Monoclonal Antibody (OTI5B6), TrueMAB
인간 GTF2B 단백질(아미노산 43-316)에 특이적인 Mouse IgG2b 단일클론 항체. Western blot에 최적화되어 있으며, 고순도 친화 크로마토그래피로 정제됨. PBS/BSA/glycerol 완충액에 보관, 연구용 전용.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5B6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 43–316 of human GTF2B produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Ubiquitin is a 76 amino acid highly conserved eukaryotic polypeptide that selectively marks cellular proteins for proteolytic degradation by the 26S proteasome. The process of target selection, covalent attachment, and transport to the proteasome regulates the concentrations of key cellular proteins by limiting their lifespans.
Polyubiquitination involves serial enzymatic steps including activation by E1, transfer to E2, and conjugation to substrates via E2 or E3 ligase. Deubiquitination enzymes reverse this process.
Posttranslational tagging by ubiquitin participates in diverse cellular processes such as cell cycle regulation, differentiation, apoptosis, DNA repair, transcription regulation, transport, stress response, immunity, and neural functions.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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