Thermo Fisher Scientific D2HGDH Polyclonal Antibody
인간 D2HGDH 단백질을 인식하는 Rabbit Polyclonal 항체로, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 0.3 mg/mL 농도의 액상 형태. PBS(glycerol 포함) 완충액에 보관하며, 연구용으로만 사용 가능.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human D2HGDH. Recombinant protein control fragment (Product # RP-108447) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2791612 |
Product Specific Information
Immunogen sequence:
VTDPEALQAP NVDWLRTLRG CSKVLLRPRT SEEVSHILRH CHERNLAVNP QGGNTGMVGG SVPVFDEIIL STARMNRVLS FHSVS
Target Information
This gene encodes D-2-hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family.
This enzyme, most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate.
Mutations in this gene are associated with D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder characterized by developmental delay, epilepsy, hypotonia, and dysmorphic features.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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