Thermo Fisher Scientific NR0B2 Polyclonal Antibody
NR0B2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 적합합니다. 고순도 항원 친화 크로마토그래피로 정제되었으며, Human 반응성 및 Mouse 예측 반응성을 가집니다. 연구용으로만 사용됩니다.
- 카탈로그번호
- PA522311
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 64–257 of NR0B2 (Uniprot ID: Q15466) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.89 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11152290 |
Product Specific Information
- Recommended positive control: 293T cells transfected with NR0B2
- Predicted reactivity: Mouse (80%)
- Store product as a concentrated solution. Centrifuge briefly before opening the vial.
Target Information
NR0B2 encodes an orphan nuclear receptor lacking a conventional DNA-binding domain but containing a ligand-binding domain. It interacts with retinoid, thyroid, and estrogen receptors, inhibiting their ligand-dependent transcriptional activation. The protein represses nuclear hormone receptor-mediated transactivation through competition with coactivators and direct transcriptional repression.
⚠ WARNING: This product contains chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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