Thermo Fisher Scientific MEMO1 Polyclonal Antibody
MEMO1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 다양한 종에 반응하며, 세포 이동 및 ERBB2 신호전달 연구에 활용됩니다. 합성 펩타이드 면역원 기반, 액상 형태로 제공되며 -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human MEMO1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2884605 |
Product Specific Information
Immunogen sequence:
AMESHKDEFT IIPVLVGALS ESKEQEFGKL FSKYLADPSN LFVVSSDFCH
- For short term use, store at 2–8°C up to 1 week.
- For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- Predicted homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%
Target Information
May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling.
The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex.
It controls the localization of APC and CLASP2 to the cell membrane, via regulation of GSK3B activity.
Membrane-bound APC allows localization of MACF1 to the cell membrane, which is required for microtubule capture and stabilization.
Is required for breast carcinoma cell migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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