Thermo Fisher Scientific ARFGAP3 Polyclonal Antibody
ARFGAP3 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF에 사용 가능. Human 및 Mouse 시료에 반응하며, 고순도의 Affinity chromatography로 정제됨. PBS/glycerol buffer에 보관되며 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ARFGAP3 (Accession Q9NP61), corresponding to amino acid residues D484–S516 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854265 |
Product Specific Information
Antibody detects endogenous levels of total ARFGAP3.
Target Information
The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. It promotes hydrolysis of ARF1-bound GTP, required for dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of coat proteins is necessary for vesicle fusion with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been identified. This gene was originally known as ARFGAP1, now referring to a related but distinct gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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