Thermo Fisher Scientific PPP2R5D Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:3,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:100–1:1,000

Product Specifications

Product Specific Information

• Recommended positive controls: HeLa, A549, IMR32, HCT116, PPP2R5D shRNA-transfected HeLa
• Predicted reactivity: Mouse (100%), Pig (100%), Rabbit (100%), Bovine (100%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass transcriptional activation or repression.
ZNF265 (Zinc finger protein 265), also known as ZRANB2 (Zinc finger Ran-binding domain-containing protein 2), ZIS, ZIS1 or ZIS2, is a 330 amino acid protein that belongs to the ZRANB2 family.
Localized to the nucleus, ZNF265 functions as a splicing factor responsible for alternatively splicing Tra-2 beta transcripts and may interfere with constitutive 5′-splice selection.
ZNF265 contains two RanBP2-type zinc fingers that convey its RNA-binding activity. Two isoforms, ZIS-1 and ZIS-2, are expressed due to alternative splicing events. Upon DNA damage, ZIS-2 may be phosphorylated by ATM or ATR.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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