Thermo Fisher Scientific ESRP1 Polyclonal Antibody
Human ESRP1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P)에서 검증됨. 항원 친화 크로마토그래피로 정제되었으며 PBS(40% glycerol) buffer에 보존. ESRP1 관련 스플라이싱 조절 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ESRP1. Recombinant protein control fragment (Product #RP-93918) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641128 |
Product Specific Information
Immunogen sequence:
PGSPNSLGYF PTAANLSGVP PQPGTVVRMQ GLAYNTGVKE ILNFFQGYQY ATEDGLIHTN DQARTLPKEW VCI
Antigen sequence identity:
- Mouse: 97%
- Rat: 97%
Target Information
RBM35A, also known as ESRP1, is an mRNA splicing factor that, together with its related protein RBM35B (ESRP2), coordinates an epithelial cell-type-specific splicing program.
RBM35A contains three putative RNA recognition motifs and binds specific sequences in mRNAs. It regulates posttranscriptional expression of genes such as FGFR2, CD44, CTNND1, and ENAH, influencing protein translation via 5′ UTRs.
Recent studies suggest RBM35A may function as a novel tumor suppressor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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