Thermo Fisher Scientific ESRP1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ESRP1. Recombinant protein control fragment (Product #RP-93918). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ESRP1,uniProtId:Q6NXG1-1,ncbiNodeId:9606,antigenRange:609-681,antigenLength:681,antigenImageFileName:PA5-54872_ESRP1_Q6NXG1-1_Rabbit.svg,antigenImageFileNamePDP:PA5-54872_ESRP1_Q6NXG1-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2641128

Product Specific Information

Immunogen sequence: PGSPNSLGYF PTAANLSGVP PQPGTVVRMQ GLAYNTGVKE ILNFFQGYQY ATEDGLIHTN DQARTLPKEW VCI

Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.

Target Information

RBM35A, also known as ESRP1, is a mRNA splicing factor that with its related protein RBM35B (ESRP2) are coordinators of an epithelial cell-type-specific splicing program. RBM35A contains three putative RNA recognition motifs and acts by directly binding specific sequences in mRNAs. RBM35A is involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5` UTRs of mRNAs. Other recent studies have shown that RMB35A may also act as a novel tumor suppressor.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.