Thermo Fisher Scientific FZD10 Polyclonal Antibody
FZD10 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 인체, 마우스, 영장류 반응성이 있으며, 합성 펩타이드 항원으로 제작되었습니다. 액상 형태로 -20°C에서 보관하며, 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human FZD10 (Accession Q9ULW2), corresponding to amino acid residues P151–V201 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899894 |
Product Specific Information
Antibody detects endogenous levels of total FZD10.
Target Information
FZD10 (Frizzled-10) is a 581 amino acid protein belonging to the G-protein coupled receptor Fz/Smo family.
It contains a signal peptide, a cysteine-rich domain in the N-terminal region, seven transmembrane domains, and a C-terminal PDZ domain-binding motif.
FZD10 is involved in signal transduction and intercellular transmission of polarity information during tissue morphogenesis in differentiated tissues, and functions as a receptor for Wnt proteins.
It is highly expressed in placenta, fetal kidney, fetal lung, brain (cerebellum, cerebral cortex, medulla, spinal cord), with low expression in adult brain, heart, lung, and skeletal muscle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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