Thermo Fisher Scientific RAB8A Recombinant Rabbit Monoclonal Antibody (JE64-79)
RAB8A 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot에 적합합니다. HEK293 세포에서 발현되었으며, 비결합형 액상 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관이 권장됩니다.
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Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JE64-79 |
| Immunogen | Synthetic peptide within human RAB8A aa 151–200/207 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Target Information
The protein encoded by this gene is a member of the RAS superfamily of small GTP/GDP-binding proteins with an average size of 200 amino acids.
RAB/YPT family proteins may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and plasma membrane.
This protein shares 97%, 96%, and 51% similarity with dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively, and contains four GTP/GDP-binding sites common to RAS proteins.
It also includes a C-terminal CAAX motif characteristic of RAS superfamily members but absent in most RAB proteins.
Although isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrated.
This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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