ELK Biotechnology IF4A3 rabbit pAb
IF4A3 단백질을 인식하는 토끼 다클론 항체로, WB 분석에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 핵 및 세포질에서 발현되는 단백질 검출에 사용됩니다. -20°C에서 1년 보관 가능합니다.
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제품명
IF4A3 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB |
| Recommended Dilutions | WB 1:500–2000 |
| Immunogen | Synthesized peptide derived from human IF4A3 (AA range: 218–268) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Gene ID (Human) | 9775 |
| Human Swiss-Prot No. | P38919 |
| Species Reactivity | Human, Mouse, Rat |
| Cellular Localization | Nucleus, Nucleus speckle, Cytoplasm. Nucleocytoplasmic shuttling protein. Travels to the cytoplasm as part of the exon junction complex (EJC) bound to mRNA. Detected in dendritic layer as well as the nuclear and cytoplasmic (somatic) compartments of neurons. Colocalizes with STAU1 and FMR1 in dendrites (By similarity). |
Background
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4AI and eIF4AII, two other members of the DEAD box protein family. (Provided by RefSeq, Jul 2008)
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