ELK Biotechnology MYT1L rabbit pAb
MYT1L rabbit pAb는 인간, 마우스, 랫트 시료에 반응하는 다클론 항체로 WB, ELISA, IHC에 적합합니다. 인간 MYT1L 유래 펩타이드로 면역화되었으며 핵 내 DNA 결합 부위에 주로 위치합니다. -20°C에서 1년 보관 가능하며 농도는 1 mg/ml입니다.
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제품명
MYT1L rabbit pAb
적용 분야
- WB (Western Blot)
- ELISA
- IHC (Immunohistochemistry)
권장 희석 배율
- WB: 1:500–2000
- IHC-p: 1:50–300
- ELISA: 1:2000–20000
제품 정보
| 항목 | 내용 |
|---|---|
| Immunogen | Synthesized peptide derived from human MYT1L (AA range: 595–645) |
| Species Reactivity | Human, Mouse, Rat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 23040 |
| Human Swiss-Prot No | Q9UL68 |
| Cellular Localization | Nucleus, Chromosome. Preferentially binds to DNA binding sites that are in an open chromatin configuration. |
| Storage | -20°C / 1 year |
Background
This gene encodes a member of the zinc finger superfamily of transcription factors. The encoded protein belongs to a novel class of cystein-cystein-histidine-cystein zinc finger proteins that function in the developing mammalian central nervous system. Forced expression of this gene in combination with the basic helix-loop-helix transcription factor NeuroD1 and the transcription factors POU class 3 homeobox 2 and achaete-scute family basic helix-loop-helix transcription factor 1 can convert fetal and postnatal human fibroblasts into induced neuronal cells, which are able to generate action potentials. Mutations in this gene have been associated with autosomal mental retardation-39 and autism spectrum disorder. Alternative splicing results in multiple variants. [provided by RefSeq, Aug 2016]
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