ELK Biotechnology NALD2 rabbit pAb
NALD2 단백질을 인식하는 토끼 다클론 항체로 WB 및 IHC에 적합. 인간 및 생쥐 시료에 반응. 합성 펩타이드 면역원 사용. 세포막 단일 통과형 II형 막단백질 표적. -20°C에서 1년 보관 가능.
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제품명
NALD2 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB; IHC |
| Recommended Dilutions | WB 1:500–2000; IHC-p 1:50–300 |
| Immunogen | Synthesized peptide derived from human NALD2 (AA range: 9–59) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Gene ID (Human) | 10003 |
| Human Swiss-Prot No. | Q9Y3Q0 |
| Cellular Localization | Cell membrane; Single-pass type II membrane protein |
| Species Reactivity | Human; Mouse |
Background
This gene is a member of the N-acetylated alpha-linked acidic dipeptidase (NAALADase) gene family. The representative member of this family is the gene encoding human prostate-specific membrane antigen (PSM), which is a marker of prostatic carcinomas and is the first to be shown to possess NAALADase activity. NAALADase cleaves N-acetyl-L-aspartate-L-glutamate (NAAG), a neuropeptide expressed both in the central nervous system and in the periphery, thought to function as a neurotransmitter. The product of this gene is a type II integral membrane protein. Transient transfection of this gene confers both NAALADase and dipeptidyl peptidase IV activities to mammalian cells. This gene is highly expressed in ovary and testis as well as within discrete brain areas. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
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