ELK Biotechnology NDUFA1 Polyclona Antibody
NDUFA1 단백질을 인식하는 토끼 다클론 항체로, IHC 및 ELISA에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 미토콘드리아 내막 단백질 복합체 I 연구에 활용됩니다. -20°C에서 1년 보관 가능합니다.
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NDUFA1 Polyclonal Antibody
제품 정보
| 항목 | 내용 |
|---|---|
| Product Name | NDUFA1 Polyclonal Antibody |
| Alternative Names | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (Complex I-MWFE; CI-MWFE; NADH-ubiquinone oxidoreductase MWFE subunit) |
| Applications | IHC; ELISA |
| Recommended Dilutions | IHC-p: 1:50–200, ELISA (peptide): 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human NDUFA1 (AA range: 20–100) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Gene ID (Human) | 4694 |
| Human Swiss-Prot No. | O15239 |
| Cellular Localization | Mitochondrion inner membrane; Single-pass membrane protein; Matrix side |
| Species Reactivity | Human; Mouse; Rat |
Background
The human NDUFA1 gene encodes an essential component of complex I of the respiratory chain, responsible for transferring electrons from NADH to ubiquinone. The N-terminal hydrophobic domain may form an alpha-helix spanning the inner mitochondrial membrane, while the C-terminal hydrophilic domain interacts with globular subunits of complex I. This conserved two-domain structure is critical for protein function, potentially anchoring the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. NDUFA1 is also part of the hydrophobic protein fraction of complex I, potentially participating in proton translocation.
[provided by RefSeq, Jul 2008]
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