ELK Biotechnology NF-κB2 p100 (phospho-Ser866/870) rabbit pAb
NF-κB2 p100 (phospho-Ser866/870) rabbit polyclonal antibody로, 인산화된 NF-κB2 단백질 검출에 적합합니다. WB에 사용 가능하며, 인간 및 마우스 시료에 반응합니다. 핵 및 세포질 내 위치 단백질 연구에 유용합니다.
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제품명
NF-κB2 p100 (phospho-Ser866/870) rabbit pAb
제품 개요
NF-κB2 p100 (phospho-Ser866/870) 항체는 인산화된 NF-κB2 단백질의 Ser866 및 Ser870 잔기를 특이적으로 인식하는 rabbit polyclonal antibody입니다. 염증 및 면역 반응 관련 유전자 발현 조절 연구에 적합합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | NF-κB2 p100 (phospho-Ser866/870) rabbit pAb |
| Alternative Names | Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2), H2TF1, Lymphocyte translocation chromosome 10 protein, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, Oncogene Lyt-10, Lyt10 [Cleaved into: Nuclear factor NF-kappa-B p52 subunit] |
| Applications | WB |
| Recommended Dilutions | WB 1:1000–2000 |
| Immunogen | Synthesized phospho peptide around human NF-κB2 p100 (Ser866 and 870) |
| Host | Rabbit |
| Storage | -20 °C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 100 kD |
| Gene ID (Human) | 4791 |
| Human Swiss-Prot No | Q00653 |
| Species Reactivity | Human, Mouse |
| Cellular Localization | Nucleus; Cytoplasm. Found in the nucleus and also in the cytoplasm in an inactive form complexed to I-kappa-B. |
Background
The nuclear factor kappa B subunit 2 (NFKB2) gene encodes a component of the NF-κB transcription factor complex, which regulates genes involved in inflammation and immune responses. The full-length p100 protein is processed into the active p52 form. Chromosomal rearrangements and translocations of this gene have been associated with B cell lymphomas, potentially forming fusion proteins. A pseudogene exists on chromosome 18, and alternative splicing produces multiple transcript variants.
(RefSeq, Dec 2013)
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