Thermo Fisher Scientific LC3B Polyclonal Antibody
LC3B 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC 등 다양한 응용에 적합합니다. 인간, 마우스, 랫트에 반응하며 자가포식 연구에 활용됩니다. 고순도 정제 및 안정적 보존 조건을 제공합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 | - |
| Immunocytochemistry (ICC/IF) | 1:100 | - |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide between amino acids 1–30 of the N-terminal region of human LC3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2552505 |
Product Specific Information
This antibody is predicted to react with bovine based on sequence homology.
Target Information
LC3B (Autophagy Marker Light Chain 3B, MAP1A/MAP1B LC3 B) is encoded by the MAP1LC3B gene in humans. LC3B is associated with microtubule assembly and plays an important role in neurogenesis. It is a key marker in autophagy, a process for the degradation of cytoplasmic components.
During autophagy, LC3 isoforms undergo post-translational modifications and participate in the formation of autophagosomes that enclose cytoplasmic material for lysosomal degradation.
LC3B is a microtubule-associated protein mediating interactions between microtubules and cytoskeletal components and may be involved in cancer, aging, metabolic, neurodegenerative, and cardiovascular/pulmonary diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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